By T. W. Sadler
the hot version is greater through over a hundred new and up to date illustrations, extra scientific pictures and images of early embryologic improvement, and an extended bankruptcy at the cardiovascular system.
- Clinical Correlates packing containers illustrated through instances and photographs conceal delivery defects, developmental abnormalities, and different medical phenomena.
- More than four hundred illustrations—including full-color line drawings, scanning electron micrographs, and medical images—clarify key facets of embryonic development.
- Basic genetic molecular biology rules are highlighted during the textual content to hyperlink embryology to different serious specialties.
- Chapter assessment figures supply a visually compelling advent to every chapter.
- Problems to unravel (with precise solutions behind the publication) assist you verify your understanding.
- An multiplied word list defines keywords and concepts.
- Online studying assets for college students comprise an interactive query financial institution and animations.
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Additional info for Langman's Medical Embriology
Capacitated sperm pass freely through corona cells (Fig. 5). PHASE 2: PENETRATION OF THE ZONA PELLUCIDA The zona is a glycoprotein shell surrounding the egg that facilitates and maintains sperm binding and induces the acrosome reaction. Both binding and the acrosome reaction are mediated by the ligand ZP3, a zona protein. Release of acrosomal enzymes (acrosin) allows sperm to penetrate the zona, thereby coming in contact with the plasma membrane of the oocyte (Fig. 5). Permeability of the zona pellucida changes when the head of the sperm comes in contact with the oocyte surface.
Contrib Embryol 36:67, 1948. c h a p t e r 2 First Week of Development: Ovulation to Implantation Ovarian Cycle At puberty, the female begins to undergo regular monthly cycles. These sexual cycles are controlled by the hypothalamus. Gonadotropin-releasing hormone (GnRH) produced by the hypothalamus acts on cells of the anterior pituitary gland, which in turn secrete gonadotropins. These hormones, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), stimulate and control cyclic changes in the ovary.
5th ed. London, Blackwell Science Limited, 2000. Jones KL (ed): Smith’s Recognizable Patterns of Human Malformation. 4th ed. Philadelphia, WB Saunders, 1988. Larsen WJ, Wert SE: Roles of cell junctions in gametogenesis and early embryonic development. Tissue Cell 20:809, 1988. Lenke RR, Levy HL: Maternal phenylketonuria and hyperphenylalaninemia: an international survey of untreated and treated pregnancies. N Engl J Med 303:1202, 1980. Pelletier RA, We K, Balakier H: Development of membrane differentiations in the guinea pig spermatid during spermiogenesis.