Aptamers: Tools for Nanotherapy and Molecular Imaging by Rakesh N. Veedu

By Rakesh N. Veedu

Aptamers, usually termed as ‘chemical antibodies,’ are an rising category of man-made ligands for effective target-specific molecular popularity. the target of this booklet is to focus on contemporary advances and capability of aptamers in a variety of affliction stipulations. . This e-book specializes in the functions of aptamers in detailed nanotherapy, detection, and in molecular imaging in a number of disorder stipulations comparable to melanoma, neurological illnesses and infectious diseases.

Show description

By Rakesh N. Veedu

Aptamers, usually termed as ‘chemical antibodies,’ are an rising category of man-made ligands for effective target-specific molecular popularity. the target of this booklet is to focus on contemporary advances and capability of aptamers in a variety of affliction stipulations. . This e-book specializes in the functions of aptamers in detailed nanotherapy, detection, and in molecular imaging in a number of disorder stipulations comparable to melanoma, neurological illnesses and infectious diseases.

Show description

Read or Download Aptamers: Tools for Nanotherapy and Molecular Imaging PDF

Similar biomedical engineering books

Basic Feedback Controls in Biomedicine (Synthesis Lectures on Biomedical Engineering)

This textbook is meant for undergraduate scholars (juniors or seniors) in Biomedical Engineering, with the most target of aiding those scholars find out about classical keep an eye on conception and its software in physiological structures. additionally, scholars will be in a position to practice the Laboratory digital Instrumentation Engineering Workbench (LabVIEW) Controls and Simulation Modules to mammalian body structure.

Characterisation and Design of Tissue Scaffolds

Characterisation and layout of Tissue Scaffolds bargains scientists an invaluable consultant at the characterization of tissue scaffolds, detailing what should be measured and why, how such measurements might be made, and addressing industrially very important concerns. half one offers readers with info at the basic issues within the characterization of tissue scaffolds, whereas different sections element how one can arrange tissue scaffolds, talk about ideas in characterization, and current useful concerns for brands.

Nanozymes: Next Wave of Artificial Enzymes

This booklet describes the basic suggestions, the most recent advancements and the outlook of the sector of nanozymes (i. e. , the catalytic nanomaterials with enzymatic characteristics). As certainly one of today’s most fun fields, nanozyme examine lies on the interface of chemistry, biology, fabrics technology and nanotechnology.

Extra info for Aptamers: Tools for Nanotherapy and Molecular Imaging

Example text

C. (2009). Evolution of a histone H4-K16 acetyl-specific DNA aptamer, J. Am. Chem. , 131, pp. 6330–6331. 30. , Qureshi, M. , Ardah, M. , Shehab, S. , and El-Agnaf, O. M. (2010). Detection of elevated levels of alpha-synuclein oligomers in CSF from patients with Parkinson disease, Neurology, 75, pp. 1766–1772. 31. , Thompson, J. , McIntire, T. , Milton, S. , Cotman, C. , and Glabe, C. G. (2003). Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis, Science, 300, pp.

564–566. 52. Tasset, D. , Kubik, M. , and Steiner, W. (1997). Oligonucleotide inhibitors of human thrombin that bind distinct epitopes, J. Mol. , 272, pp. 688–698. 53. , Lis, J. , and Shi, H. (2013). , 23, pp. 238–242. 54. , and Tan, W. (2008). Molecular assembly for highperformance bivalent nucleic acid inhibitor, Proc. Natl. Acad. Sci. U S A, 105, pp. 5664–5669. 55. , and Heyduk, T. (2009). Bivalent ligands with long nanometerscale flexible linkers, Biochemistry, 48, pp. 264–275. 56. Ahmad, K.

Sci. U S A, 104, pp. 14664– 14669. 78. , Kumar, J. -Y. (2015). Computational selection of RNA aptamer against angiopoietin-2 and experimental evaluation, Biomed Res. , 2015, p. 658712. 79. , Sauna, Z. , and Przytycka, T. M. (2012). Identification of sequence-structure RNA binding motifs for SELEX-derived aptamers, Bioinformatics, 28, pp. i215–i223. 80. , Propson, N. , Soh, H. , Thomson, J. , and Stewart, R. (2014). MPBind: a meta-motif-based statistical framework and pipeline to predict binding potential of SELEX-derived aptamers, Bioinformatics, 30, pp.

Download PDF sample

Rated 4.00 of 5 – based on 43 votes