By Hao Da, Xiao Jie Gu, Pei Gen Xiao
Medicinal crops: Chemistry, Biology and Omics studies the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of chosen medicinal plant tribes and genera, and their relevance to drug efficacy.
Medicinal crops supply a myriad of pharmaceutically energetic parts, which were common in conventional chinese language drugs and world wide for millions of years. expanding curiosity in plant-based medicinal assets has ended in extra discoveries of many novel compounds, in a variety of angiosperm and gymnosperm species, and investigations on their chemotaxonomy, molecular phylogeny and pharmacology.
Chapters during this e-book discover the interrelationship inside of conventional chinese language medicinal plant teams and among chinese language species and species outdoors of China. Chapters additionally talk about the incongruence among chemotaxonomy and molecular phylogeny, concluding with chapters on structures biology and -omics applied sciences (genomics, transcriptomics, proteomics, and metabolomics), and the way they're going to play an more and more vital function in destiny pharmaceutical learn.
• stories top perform and crucial advancements in medicinal plant chemistry and biology
• Discusses the foundations and purposes of assorted recommendations used to find medicinal compounds
• Explores the research and category of novel plant-based medicinal compounds
• comprises case reports on pharmaphylogeny
• Compares and integrates conventional wisdom and present belief of globally medicinal crops "
About the Authors
Dr. Da Cheng Hao is an affiliate Professor and precept investigator on the university of setting and Chemical Engineering, dependent on the Biotechnology Institute, Dalian Jiaotong college, Dalian, P.R China. he's a visitor Prof. of Institute of Medicinal Plant improvement (IMPLAD), chinese language Academy of clinical Sciences (CAMS), Beijing, P. R China.
Dr. Xiao Jie Gu is a Lecturer on the university of atmosphere and Chemical Engineering, established on the Biotechnology Institute, Dalian Jiaotong college, Dalian, P.R China.
Professor Pei Gen Xiao is an Academician of chinese language Academy of Engineering and the top of Key Laboratory of Bioactive ingredients and assets usage of chinese language natural medication, Ministry of schooling, dependent at IMPLAD, CAMS, Beijing, P. R China.
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Extra resources for Medicinal Plants: Chemistry, Biology and Omics
Example text
NCBI GenBank accession number is shown in front of taxon name. , 2012a), which can be used to unambiguously identify 38 samples of different origins. A rapid reversed-phase (RP) HPLC method was developed and applied for simultaneous separation and the determination of flavonoids and phenolic acids in eight Plantago (Plantaginaceae) taxa (P. altissima, P. argentea, P. coronopus, P. holosteum ssp. depauperata, P. holosteum ssp. holosteum, P. holosteum ssp. scopulorum, P. lagopus, and P. , 2013). The contents of the analyzed phenolic compounds (% of the dry weight of the leaves, dw) varied among species: rutin (max.
Rockii, P. jishanensis, P. decomposita, P. delavayi, and P. , 2014). Forty-seven peaks exhibited an occurrence frequency of 75% in all 23 tree peony samples, 43 of which were identified according to their retention times and UV absorption spectra, together with combined HPLC–QTOF-MS. The 43 isolated compounds included 17 monoterpenoid glucosides, 11 galloyl glucoses, 5 flavonoids, 6 paeonols, and 4 phenols. C. C. Stern with the exception of P. decomposita, a transition species between these subsections.
The investigation of H2O extracts by LC–MS/MS revealed the presence of depside constituents. In M. perennis, a mixture of mercurialis acid (2R-(E-caffeoyl)-2-oxoglutarate) and phaselic acid (E-caffeoyl-2-malate) could be detected; in M. annua, only phaselic acid was found. The configuration of the depside could be 2S in M. annua and 2R in M. perennis. , 2013) or even subfamily Aquilarioideae. Flavonoids, diterpenes, and triterpenes are also useful in chemotaxonomy of Aquilaria. Chemotaxonomy: a phylogeny-based approach 25 Cannabinoids are terpenophenolic compounds unique to Cannabis (Cannabaceae).