Meningococcal Vaccines: Methods and Protocols (Methods in by Andrew J. Pollard, Martin C.J. Maiden

By Andrew J. Pollard, Martin C.J. Maiden

Andrew Pollard and Martin Maiden have assembled a magnificent number of the most recent molecular and mobile ideas for the improvement, overview, and implementation of vaccines for use in contrast dreaded disorder. The contributors-leading scientists, clinicians, and public wellbeing and fitness physicians-describe intimately the numerous ways to vaccine layout, in addition to the review of immune reaction to vaccine applicants and novel vaccine formulations. well timed and entire, Meningococcal Vaccines: equipment and Protocols offers the scientist, public health and wellbeing surgeon, epidemiologist, medical microbiologist, and clinician with the basic instruments to put naked the secrets and techniques of the meningococcus, and to increase, evaluation, and enforce profitable new meningococcal vaccines.

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By Andrew J. Pollard, Martin C.J. Maiden

Andrew Pollard and Martin Maiden have assembled a magnificent number of the most recent molecular and mobile ideas for the improvement, overview, and implementation of vaccines for use in contrast dreaded disorder. The contributors-leading scientists, clinicians, and public wellbeing and fitness physicians-describe intimately the numerous ways to vaccine layout, in addition to the review of immune reaction to vaccine applicants and novel vaccine formulations. well timed and entire, Meningococcal Vaccines: equipment and Protocols offers the scientist, public health and wellbeing surgeon, epidemiologist, medical microbiologist, and clinician with the basic instruments to put naked the secrets and techniques of the meningococcus, and to increase, evaluation, and enforce profitable new meningococcal vaccines.

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Dis. 165(Suppl. 1), S167–S176. 14. Hamadeh, R. , and Griffiss, J. M. (1995) Anti-alphagalactosyl immunoglobulin A (IgA), IgG, and IgM in human secretions. Clin. Diagn. Lab. Immunol. 2, 125–131. 15. Jarvis, G. A. and Griffiss, J. M. (1991) Human IgA1 blockade of IgG-initiated lysis of Neisseria meningitidis is a function of antigen-binding fragment binding to the polysaccharide capsule. J. Immunol. 147, 1962–1967. 16. , and Kondoh, H. (1987) Resistance of normal serum IgA and secretory IgA to bacterial IgA proteases: evidence for the presence of enzyme-neutralizing antibodies in both serum and secretory IgA, and also in serum IgG.

9. Wyle, F. , Artenstein, M. , Brandt, B. , Tramont, E. , Kasper, D. , Altieri, P. , et al. (1972) Immunologic response of man to group B meningococcal polysaccharide vaccines. J Infect. Dis. 126, 514–521. 10. , and Makela, P. H. (1983) Antigenic similarities between brain components and bacteria causing meningitis: implications for vaccine development and pathogenesis. Lancet ii, 355–357. 11. Poolman, J. T. (1995) Development of a meningococcal vaccine. Infect. Agents Dis. 4, 13–28. 12. Zollinger, W.

Microbiology 144, 3027–3037. Christodoulides, M. and Heckels, J. E. (1994) Immunization with a multiple antigen peptide containing defined B- and T-cell epitopes: production of bactericidal antibodies against group B Neisseria meningitidis. Microbiology 140, 2951–2960. , Borriello, S. , and Ala’Aldeen, D. A. (1999) Identification and characterization of TspA, a major CD4(+) T-celland B-cell-stimulating Neisseria-specific antigen. Infect. Immun. 67, 3533–3541. Immune Response 23 2 Immune Response and Host–Pathogen Interactions Andrew J.

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