By Thomas Muir
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Early research has demonstrated that SFB had an important role in the immunology of their hosts. However, the unculturability of SFB has made many studies of this organism’s unique features impossible. Mono-colonized mice with SFB allow the opportunity to further exploit the organism’s unique characteristics. Recent reports indicated that SFB could stimulate the development of germinal center reactions in the Peryer’s patches, induce the expression of CD4+ T-cell and IgA. The latest study has found that SFB can induce the expression of pro-inflammatory factors by comparing mice from differing sources.
The supplementary use of probiotics aims at restoring the intestinal microecological balance, repairing the enterobacteria membrane barrier, improving intestinal planting resistance, inhibiting excessive growth of potential pathogenic bacteria, promoting the secreting mucins of intestinal epithelial cells, secreting sIgA of paneth cells regulating the body’s immune function and so on [15,16]. 4 The Classification of Infection The classification of infection can be defined in different ways according to the origin of pathogens.
In the 1970s, Dr. Volker Rush from Germany first proposed the word “microecology”. He stated that “microecology is ecology on a cellular or molecular level”, and established the first microecology institute in the world, in Holborn. This was the first time that microecology appeared as a concept. 2 History of Infectious Microecology 7 then, with the use of anaerobic culture, electron microscopy, cell and molecular biology in the research field of microecology, microecological research maderapid advancement.