Atlas of the Mammalian Ovary: Morphological Dynamics and by Katharina Spanel-Borowski

By Katharina Spanel-Borowski

In the period of molecular biology, an atlas that permits a speedy realizing of the complexity of ovarian methods is urgently wanted. during this e-book, the writer attracts upon her personal learn, carried out during the last 3 many years, to supply a different compilation of fine quality illustrations that provide illuminating insights in a with ease available shape. The ovarian follicles, the corpus luteum, and the interstitial cortex are offered as accurately managed homeostatic cubicles. Physiologic mobile demise varieties and leukocyte subtypes are in actual fact depicted, and a few of the steps within the ovulatory strategy are confirmed intimately. additional themes addressed comprise the microvascular mattress, the plasticity of intraovarian nerves as a part of the remodelling strategies within the polycystic and the menopausal ovary, and the position of cytokeratin-positive cells as messengers of innate immunity. This atlas might be a desirable and informative source for either trainees and more matured professionals.

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By Katharina Spanel-Borowski

In the period of molecular biology, an atlas that permits a speedy realizing of the complexity of ovarian methods is urgently wanted. during this e-book, the writer attracts upon her personal learn, carried out during the last 3 many years, to supply a different compilation of fine quality illustrations that provide illuminating insights in a with ease available shape. The ovarian follicles, the corpus luteum, and the interstitial cortex are offered as accurately managed homeostatic cubicles. Physiologic mobile demise varieties and leukocyte subtypes are in actual fact depicted, and a few of the steps within the ovulatory strategy are confirmed intimately. additional themes addressed comprise the microvascular mattress, the plasticity of intraovarian nerves as a part of the remodelling strategies within the polycystic and the menopausal ovary, and the position of cytokeratin-positive cells as messengers of innate immunity. This atlas might be a desirable and informative source for either trainees and more matured professionals.

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Atlas of the Mammalian Ovary: Morphological Dynamics and Potential Role of Innate Immunity

Within the period of molecular biology, an atlas that enables a quick realizing of the complexity of ovarian strategies is urgently wanted. during this ebook, the writer attracts upon her personal learn, carried out over the last 3 many years, to supply a different compilation of high quality illustrations that supply illuminating insights in a with no trouble obtainable shape.

Additional info for Atlas of the Mammalian Ovary: Morphological Dynamics and Potential Role of Innate Immunity

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Clones are positive for CD18, and they display activity of 3b-hydroxysteroid dehydrogenase and of alkaline phosphatase (Fig. 15a–f). Uptake of horseradish peroxidase speaks for the presence of macrophages (Fig. 15f). Progenitor cell markers such as Sox-2, Oct3/4, KIT, and CD14 are consistently present in clones (Fig. 15g, h). Progenitor cells probably represent the small cells of less than 10 mm in diameter at the ultrastructural level (Fig. 16). Collectively, angiogenesis, different cell death forms, leukocyte immigration, and the recruitment of progenitor cells fit into an acute inflammatory response being carefully mediated by the Myd88-related pathway of multipurpose INIM function (Takeda and Akira 2005; Takeuchi and Akira 2010; O’Neill and Bowie 2007).

ISBN 978-3-642-16076-9 Spanel-Borowski K (2011b) Ovulation as danger signaling event of innate immunity. Mol Cell Endocrinol 333:1–7 Spanel-Borowski K, Ricken AM (1997) Varying morphology of bovine granulosa cell cultures. In: Motta M (ed) Microscopy of reproduction and development: a dynamic approach. Antonio Delfino, Rome, pp 91–100 Spanel-Borowski K, Trepel F, Schick P, Pilgrim C (1981) Aspects of cellular proliferation during follicular atresia in the dog ovary. Cell Tissue Res 219:173–183 Spanel-Borowski K, Rahner P, Ricken AM (1997) Immunolocalization of CD18-positive cells in the bovine ovary.

12c, d). In the early stage of cell death, characteristic autophagosomes with a double unit membrane around organelle debris can be erroneously taken as pentalaminar annular junctions. They represent internalized gap junctions of preovulatory granulosa cells (Spanel-Borowski and Sterzik 1987) (Fig. 13a–c). Autophagosomes in still-intact granulosa cells indicate the struggle for survival through reparative autophagy (Klionsky 2007; Klionsky 2009; Chen and Klionsky 2011). When the survival program gets out of control, cell death autophagy ensues.

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