By Huabei Jiang
''Based on close to infrared optical applied sciences and model-based inverse computations, DOT is an imaging technique that could supply spatial distributions of intrinsic tissue optical homes via model-based reconstruction algorithms utilizing NIR measurements alongside or close to the boundary of tissue. This e-book covers virtually each point of DOT--from arithmetic, reconstruction algorithms, instrumentation, and phantom experiments to scientific purposes. The textual content covers the basics rules of DOT, together with its mathematical foundations and computational tools, and explains tips on how to arrange experimental photograph platforms, in addition to the right way to translate laboratory experiences into scientific applications''--Provided by way of publisher. Read more...
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Extra info for Diffuse optical tomography : principles and applications
This has important implications, because realistic contrast levels between tumor and normal tissue are believed to be in the range of the lower contrasts studied here (Peters et al. 1990; also Chapter 8). The large artifacts in the higher contrast level cases could be a result of breakdown of the perturbation expansion in the reconstruction algorithm or breakdown in first-order diffusion theory at the interface between drastically distinct optical media. Evaluations of our reconstruction algorithm in terms of the effects of modulation frequency have been made using both simulated and experimental data.
A Compact, ParallelDetection Diffuse Optical Mammography System, Review of Scientific Instruments, 74, 2836– 2842.
A 25-mm diameter transparent tube (50-µm thickness) containing different concentrations of Intralipid and India ink was used to simulate heterogeneities. 006 mm–1, while different contrast levels (2:1, 5:1, and 10:1 for both µs ′ and µa ) between the heterogeneity and the background have been studied. These values are similar to those for human soft tissues, especially because they are scaled relative to the geometric size of the phantom, which is large compared to typical breast dimensions. Measurements for both centered and off-centered (10 mm offset along the horizontal axis at 3 o’clock) heterogeneities have been conducted.