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Additional info for Mifepristone - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
2003 September; 80 Suppl 2: 776-82. cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=14505753 • Additive effect of mifepristone and tamoxifen on apoptotic pathways in MCF-7 human breast cancer cells. Author(s): El Etreby MF, Liang Y, Wrenn RW, Schoenlein PV. Source: Breast Cancer Research and Treatment. 1998 September; 51(2): 149-68. cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=9879777 • Advanced cervical pregnancy: uterus-sparing therapy initiated with a combination of methotrexate and mifepristone followed by evacuation and local hemostatic measures.
It has become increasingly apparent that the cellular level of the steroid receptor and the antagonist are not the only factors that determine biological response. Steroid receptor interaction with co-regulatory proteins such as co-activators, co-repressors and other transcription factors are important determinants of the final receptor activity. Because steroid receptor antagonists exhibit varying degrees of hormone agonist activity dependent on cell/tissue type and physiological state of the cell, we hypothesize that the relative agonist/antagonist activity exhibited by these compounds is controlled by Studies 27 the cellular level of expression, or availability, of these other receptors interacting proteins.
Cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=10548623 • Contraceptive efficacy of low doses of mifepristone. Author(s): Marions L, Danielsson KG, Swahn ML, Bygdeman M. Source: Fertility and Sterility. 1998 November; 70(5): 813-6. cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=9806558 • Contraceptive potential of a mifepristone-nomegestrol acetate sequential regimen in women. Author(s): Croxatto HB, Salvatierra AM, Fuentealba B, Massai R. Source: Human Reproduction (Oxford, England). 1998 December; 13(12): 3297-302.