By Dmitry I. Nurminsky
Selective Sweep bargains with the idea and perform of detection of contemporary adaptive evolution on the genomic point from the styles of DNA polymorphism. contemporary advances in genomic sequencing give you the heritage for research of polymorphic websites in huge chromosomal areas or maybe in complete genome, therefore supplying the instrument for powerful identity of loci which are below powerful strain of confident choice. as a result, the reports of selective sweep, which previously have been of curiosity typically to evolutionists, became well known and preferred via the massive organic group curious about identity of the pursuits of choice in the course of speciation, host/pathogen interactions, and resistance to chemical brokers.
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Extra resources for Selective Sweep
Sample text
This sequence matches the TSE of the testis-specific betaTub85D promoter in 21/27 bp. Yet the Sdic TSE appears to derive from the 3' UTR of AnnX, in which there is a sequence that matches in 22/27 bp. 37 Although the Sdic protein includes the carboxyl end of Cdic, it is missing 84 amino acids from the amino-terminal end of Cdic. Instead, the Sdic amino-terminus consists of a novel exon that derives largely from Cdic intron 3. 37 As diagrammed in Figure 1, transcription of Sdic begins in the PCE.
Inferring weak selection from patterns of polymorphism and divergence at “silent” sites in Drosophila DNA. Genetics 1995; 139:1067-76. Selective Sweep in the Evolution of a New Sperm-Specific Gene in Drosophila 31 4. Akashi H. Molecular evolution between Drosophila melanogaster and D. simulans: Reduced codon bias, faster rates of amino acid substitution, and larger proteins in D. melanogaster. Genetics 1996; 144:1297-307. 5. Andolfatto P, Przeworski M. Regions of lower crossing over harbor more rare variants in African populations of Drosophila melanogaster.
Genetics 1993; 134:1289-1303. 22 Selective Sweep CHAPTER 3 Selective Sweep in the Evolution of a New Sperm-Specific Gene in Drosophila Rob J. Kulathinal, Stanley A. Sawyer, Carlos D. Bustamante, Dmitry Nurminsky, Rita Ponce, José M. Ranz and Daniel L. Hartl Abstract T he Sdic gene cluster at the base of the X-chromosome is unique to the lineage of Drosophila melanogaster. The repeating unit in the cluster was formed from a duplication and fusion of the genes, AnnX and Cdic, which juxtaposed the 3' untranslated region of AnnX to the third intron of Cdic.