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Neurochem. 21, 1127-1138 (1973) 16. : Selective vulnerability of the blood-brain barrier in chemically induced lesions. J. Neuropath. expo Neurol. 25, 542-559 (1966) 17. : Mortality and morbidity from serial seizures. Epilepsia 15, 155-176 (1974) 8. An Ultrastructural Substrate for the Resolution of Post-Irradiation Brain Edema J. Cerv6s-Navarro, U. Christmann, and S. Sasaki Department of Neuropathology, Klinikum Steglitz, Free University Berlin, Berlin, W. Germany Sununary Studies were carried out on 24 Macaca muZatta monkeys which were sacrificed from 6 h to 6 days following irradiation of one hemisphere.
Lajtha, A. ). New York: Plenum Press 1976. (Advances in Experimental Medicine and Biology, Vol. LXIX), pp. 517-527 7. : Some factors influencing the damaging effect of acute arterial hypertension on cerebral vessels in rats. In: Proc. 4th Meeting Internat. Soc. of Hypertension. E. ). Clin. Sci. molec. Med. Suppl. In press (1976) 31 8. : The effect of acute arterial hypertension on the blood brain barrier to protein tracers. Acta neuropath. (Berlin) 16, 117-124 (1970) 9. : The pathophysiology of the blood-brain barrier lesions induced by experimental seizures and by severe hypercapnia.
A. Archives of Neurol. Psychiat. 69, 140 (1953) 17. : A simplified lead citrate stain for use in electron microscopy. J. Cell. Bioi. ~, 407-410 (1965) 7. The Blood-Brain Barrier in Experimental Seizures C. K. Petito, J. A. Schaefer, and F. Plum Departments of Pathology (Neuropathology) and Neurology, The New York Hospital, Cornell University Medical Center, New York, N. , USA Sununary Our studies have indicated that (1) micropinocytosis plays a major role in the increased permeability of the blood-brain barrier (BBB) during seizures, (2) seizure-induced hypertension causes most of the barrier breakdown and enhanced micropinocytosis, and (3) under these conditions there is no evidence of cerebral edema in the areas of obvious BBB breakdown.