By Institute of Medicine, LeighAnne M. Olsen, Elizabeth G. Nabel, J. Michael McGinnis, Mark B. McClellan
Drawing at the paintings of the Roundtable on Evidence-Based drugs, the 2007 IOM Annual assembly assessed a number of the quickly taking place alterations in healthiness care regarding new diagnostic and therapy instruments, rising genetic insights, the advancements in details expertise, and healthcare charges, and mentioned the necessity for a more robust specialize in proof to make sure that the promise of medical discovery and technological innovation is successfully captured to supply the best deal with the appropriate sufferer on the correct time. As new discoveries proceed to extend the universe of scientific interventions, remedies, and techniques of care, the necessity for a extra systematic method of facts improvement and alertness turns into more and more severe. with no higher information regarding the effectiveness of other treatments, the ensuing uncertainty may end up in the supply of providers which may be pointless, unproven, or perhaps destructive. bettering the evidence-base for drugs holds nice strength to extend the standard and potency of treatment. the once a year assembly, hung on October eight, 2007, introduced jointly a few of the nation's top experts on a number of features of the problems - either demanding situations and possibilities - to give their views and interact in dialogue with the IOM membership.
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Extra resources for Evidence-Based Medicine and the Changing Nature of Healthcare: 2007 IOM Annual Meeting Summary (Learning Healthcare Systems)
Paul noted that only about 50 percent of patients respond to any given therapy, and many of these do not respond in the same way. This increased focus on outcomes has put a burden on biopharmaceutical research development in terms of both longer development timelines and overall costs. To contend with this changing environment, biopharmaceutical companies are exploring the concept of tailored drug therapies: the right drug, for the right patient, at the right dose and the right time. For years, medicines have been tailored using biomarkers such as blood pressure, LDL (low-density lipoprotein) cholesterol levels, and hemoglobin A1c, but new tools for discovery and development are accelerating movement toward personalized medicine.
Caregivers can gain up-to-the-minute information on which treatments are working for which patients with just-in-time learning and searches within EHRs. In the future, providers could even examine genetic correlations. Some examples of important research facilitated by EMRs at Kaiser Permanente include the recognition of adverse effects of Vioxx in certain patients and the identification of adverse reactions in patients a number of years after treatment with heart stents. Medical records provide great potential in terms of follow-up studies and longitudinal data.
Fisher, E. , D. E. Wennberg, T. A. Stukel, D. J. Gottlieb, F. L. Lucas, and E. L. Pinder. 2003. The implications of regional variations in Medicare spending. Part 1: The content, quality, and accessibility of care. Annals of Internal Medicine 138(4):273-287. Institute of Medicine’s Roundtable on Evidence-Based Medicine. 2006. Charter. http://www. aspx (accessed May 15, 2008). Sirovich, B. , D. J. Gottlieb, H. G. Welch, and E. S. Fisher. 2006. Regional variations in health care intensity and physician perceptions of quality of care.