By John H. Laragh (auth.), John H. Laragh M.D., Fritz R. Bühler M.D., Donald W. Seldin M.D., M.A.C.P. (eds.)
reached complete definition within the Forties via Kempner nutrition. the $64000 position of adrenal aldosterone and colleagues in demonstrating the valuable ef secretion in assisting human high blood pressure is now fects of a low salt rice nutrition for treating hypertensive good well-known as are the precious results of sufferers. It grew to become obvious that the worth of rice blockade, specifically in low-renin sufferers who ex was once entirely concerning its sodium content material. A rice hibit irrelevant or absolute excesses of aldoste vitamin, or the other stringent low sodium nutrition, rone secretion. extra definition of the extra sub drastically improves or thoroughly corrects the hyper tle participation of aldosterone and of the criteria rigidity of approximately ~ or so of all sufferers with essen that regulate aldosterone secretion in hypertensive topics are promising components for additional examine. tial high blood pressure. despite the fact that, what's usually forgotten is that very little gain accrues to the rest THE fearful process majority of sufferers. Parallel stories of animal versions has demon in addition to the endocrine and excretory capabilities of strated the amplifying impression of a excessive sodium vitamin the kidney and the effect of nutritional sodium on blood strain and vice versa. traces of rats and of aldosterone secretion, there was lengthy have been built that are specifically delicate to status contract in regards to the very important position of the pressor results of a excessive sodium vitamin. In a fashion, the fearful procedure in blood strain control.
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M. D. M. U 36 Paris, France P. D. A. D. D. G. D. D. D. James J. Y. A. D. A. Nicolas D. D. A. B. D. S. P. P. D. Division of Nephrology and Hypertension Centre Hospitalier Universitaire Lausanne, Switzerland Contributors Myron H. D. A. E. D. A. Thomas A. D. A. D. University of Hokkaido Hokkaido, Japan J. D. Research Associate Department of Internal Medicine University of Mainz Mainz, Germany Frontiers in Hypertension Research: Past, Present and Future Introduction John H. Laragh THE PHENOMENON A lot has happened since 1895 when Riva-Rocci developed the first practical means for routine blood pressure measurements in the clinical setting.
D. A. D. D. G. D. D. A. N. A. D. D. Y. A. Trefor O. S. Sc. P. J. D. D. Instructor of Biochemical Pathology Shimane Medical University Chief, Biochemical Section Japan Stroke Prevention Center Izumo, Japan lng-Marie Nilsson University of Goteborg Goteborg, Sweden Miguel A. D. A. D. L. B. Senior Registrar MRC Blood Pressure Unit and Department of Medicine Western Infirmary Glasgow, Scotland Motilal B. D. A. Judith M. Sc. D. Associate Professor of Medicine Department of Internal Medicine University of Mainz 6500 Mainz, Germany James A.
Kidney and adrenal diseases), the very large residuum was termed "essential" or idiopathic hypertension. It was widely assumed that this biophysical deviation was a single disease. However, it was recognized very early that the function or survival of most people having untreated high blood pressure was not affected appreciably, if at all. " Indeed this benign characteristic of the disorder was emphasized in writings of Homer Smith, Perera, Goldring, and Chasis. Early on, however, it also became appreciated that, on a statistical basis, having a relatively higher blood pressure even within the normal range is on average clearly associated with a shortened survival.