Recent Advances in Research on the Human Placenta by J. Zheng

By J. Zheng

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By J. Zheng

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Of these, 50 placentas and 32 fetal membranes were collected in the Copper Basin and 38 placentas and 36 fetal membranes in the Carpathian Mountains – the control region. To avoid the seasonal variations in metal content, all of the samples were obtained during the autumn. The clinical characteristics of the studied groups are detailed in table 5. 36 Recent Advances in Research on the Human Placenta optical density degrees Upper Silesia 150 125 100 75 50 25 0 1986 1988 1990 1992 1994 1996 1998 2000 2002 cytochrome c oxidase trendline LDH-5 trendline Upper Silesia 140 120 100 80 60 40 20 0 1986 1988 1990 1992 1994 1996 1998 2000 2002 CCO in optical degrees class1of villi % IVS % trendline of CCO trendline of class 1 Fig.

The data elaborated in those years by Prof. Niweliński and Dr. Zamorska, pioneers of placental biomonitoring in Poland, have been handed over to the corresponding institution and finally contributed to the closure of the smelter in the 1980s. This was the first case of immobilization of the smelter as a result of social and scientific world protests in Poland. Many striking enzymatic and structural differences that were observed between the placentas of the Skawina women and those collected in mountainous, non-polluted regions of southern Poland, encouraging the use of the human placenta in the further monitoring of environmental pollution.

4, fig. 9), and the LDH-5 activity (tab. 4, fig. 2950 LDH-5 vs class 1 (%) Table 4. List of Pearson correlations for findings from Upper Silesia samples. dimensional terminal villi (tab. 4, fig. 9). On the other hand, in the control placentas the LDH-5 activity correlated negatively with small dimensional terminal villi. It is worth noting that the introduction of improved industrial technology and of unleaded fuel over the last 20 years (fig. 10) has led to an increase in the levels of cytochrome c oxidase and LDH-1 activity in placentas from Upper Silesia regions .

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